Drug resistant HIV increasing in North America

BMJ 2002; 325 doi: (Published 24 August 2002) Cite this as: BMJ 2002;325:408
  1. Janice Hopkins Tanne
  1. New York

    People recently infected with HIV are more likely to have a drug resistant virus than people infected in the mid-1990s, says a new study.

    Resistance to antiretroviral drugs increased from 3.4% during 1995-8 to 12.4% in 1999-2000. In patients with resistant strains, antiretroviral therapy took longer to suppress the virus and failed sooner. The authors recommend testing for drug resistance before treatment is started so that the most effective regimen can be chosen (New England Journal of Medicine2002;347:385-94)

    The study included 377 people from eight US and two Canadian cities who had symptoms of acute HIV seroconversion syndrome or evidence of recent HIV infection. Patients gave a plasma …

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