Oestrogen only HRT increases risk of ovarian cancer

BMJ 2002; 325 doi: (Published 27 July 2002) Cite this as: BMJ 2002;325:180
  1. Deborah Josefson
  1. Nebraska

    Women taking oestrogen only hormone replacement therapy (HRT) for 10 years or more face a 60% greater risk of developing ovarian cancer than if they had never taken it, a new study shows (JAMA 2002;288:334-41)

    The study follows recent research implicating HRT in small increased risks of cardiovascular disease, breast and uterine cancers, blood clots, and stroke. HRT is used by an estimated 13.5 million women in the United States—nearly eight million take oestrogen only pills and around six million take the combined oestrogen and progestogen form.

    Dr James Lacey …

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