Decoding of soil bacterium genome points way to new antibioticsBMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7347.1176/d (Published 11 May 2002) Cite this as: BMJ 2002;324:1176
- Susan Mayor
A British consortium of scientists has decoded the complete genome sequence of Streptomyces coelicolor A3(2), a common soil bacterium that is the source of more than two thirds of the antibiotics in current use and the harmless relative of the causative organisms for tuberculosis, leprosy, and diphtheria.
The results have shown clusters of genes with the potential for producing new antibiotic agents.
S coelicolor is a soil dwelling, filamentous bacterium responsible for producing most of the natural antibiotics used in human and veterinary medicine today. Researchers working at the Wellcome Trust Sanger Institute, the John Innes Centre, and the …