“Bubble baby” lives a normal life after gene therapy

doi:10.1136/bmj.324.7342.872

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Owen Dyer

London

The first success for gene therapy in the United Kingdom has restored health to an infant who last year was confined to a sterile room and needed to be kept alive by a ventilator.

Rhys Evans, now 18 months old, suffered from X chromosome linked severe combined immunodeficiency disorder, popularly known as “baby in the bubble” syndrome, after the sterile plastic spheres used to protect some babies from infection. He now lives a normal life at home.

At a …