Neuroblastoma screening does not reduce mortality

BMJ 2002; 324 doi: (Published 13 April 2002) Cite this as: BMJ 2002;324:867
  1. Annette Tuffs
  1. Heidelberg

    Two studies from Canada and Germany published last week provide clear evidence that children aged 1 year or younger should not be screened for neuroblastoma, because mortality is not reduced by mass screening (New England Journal of Medicine 2002;346:1041-6 and 1047-53).

    On the contrary, screening may have adverse effects, the researchers say, because it detects early cases of the tumour that probably would have remitted spontaneously without treatment. The German study reported three deaths that were due to …

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