Adult stem cells may not be able to differentiate into other cell typesBMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7339.696 (Published 23 March 2002) Cite this as: BMJ 2002;324:696
- Susan Mayor
The ability of adult stem cells to differentiate and proliferate into different cell types has been questioned in research published online last week indicating that they might simply fuse with existing cells, creating genetically mixed cells of questionable medical value.
A group working at the University of Edinburgh tracked the fate of mouse brain cells that were co-cultured with embryonic stem cells. Initial examination indicated that the adult brain cells had reverted to the less specialised status of the undifferentiated stem cells around them. However, the group, whose study appears in the web version of Nature (13 March 2002, http://dx.doi.org/10.1038/nature729), found that the new cells carried transgenic marker …