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Assisted reproduction increases risk of birth defects, study says

BMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7338.633/b (Published 16 March 2002) Cite this as: BMJ 2002;324:633
  1. Scott Gottlieb
  1. New York

    Babies born through assisted reproduction may have a nearly 1 in 10 risk of major birth defects—twice the risk among babies born naturally.

    Fertility experts were quick to caution that these findings contradict smaller studies that failed to find any increased risk of birth defects from the procedures. They said new studies would be needed to confirm the 1 in 10 risk.

    In a study published in the New England Journal of Medicine (2002;346:725-30) Dr Jennifer Kurinczuk, at the time a researcher at the Institute for Child Health Research at the University of Western Australia in Perth, and colleagues looked at the rate of major defects in babies …

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