MinervaBMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7336.554 (Published 02 March 2002) Cite this as: BMJ 2002;324:554
Compliance with eradication treatment for Helicobacter pylori might improve with shorter courses. A new short term regimen of amoxicillin, clarithromycin, and lansoprazole or ranitidine for five days (or the same antibiotic-lansoprazole combination for three days, with a two day pretreatment with lansoprazole) achieved overall eradication of 86.4% in 243 patients, all of whom finished the course. Eradication failure was associated with younger age (under 55) and having a history of peptic ulcer disease (Archives of Internal Medicine 2002;162:153-60).
Evidence from a Danish prospective cohort suggests that pregnant women who drink a moderate level of alcohol are at a higher risk of a stillbirth (American Journal of Epidemiology 2002;155:305-12). Women consuming five or more drinks a week had three times the risk of stillbirth compared with women who had less than one drink a week. Stillbirths due to fetoplacental dysfunction increased from 1.37 per 1000 births for women who had less than one drink a week, to 8.83 per 1000 births for women consuming more than five drinks a week.
A nurse led chronic pain clinic set up to help general practitioners in Belfast revealed that 54% of patients taking regular non-steroidal anti-inflammatory drugs were at risk of gastropathy from their medication. These …