Changes in the brain may link Alzheimer's and Parkinson's diseasesBMJ 2001; 323 doi: https://doi.org/10.1136/bmj.323.7316.771 (Published 06 October 2001) Cite this as: BMJ 2001;323:771
- Scott Gottlieb
- New York
Researchers have identified a common pathway in the brain for both Alzheimer's disease and Parkinson's disease, supporting clinical observations of the simultaneous appearance of symptoms of both in some patients.
The β amyloid peptides that accumulate in Alzheimer's disease plaques also increase the build up of the α synuclein protein, which is characteristic of the brains of patients with Parkinson's disease, according to Dr Eliezer Masliah from the University of California at San Diego in La Jolla, and colleagues. The potential connection suggests that experimental drugs designed to target brain deposits linked …