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Drugs for malaria and psychosis may offer hope to people with CJD

BMJ 2001; 323 doi: https://doi.org/10.1136/bmj.323.7310.416b (Published 25 August 2001) Cite this as: BMJ 2001;323:416
  1. Deborah Josefson
  1. San Francisco

    Doctors at the University of California in San Francisco are starting clinical trials for Creutzfeldt-Jakob disease (CJD) and variant CJD (vCJD) with quinacrine and chlorpromazine, after finding that the drugs inhibited the propagation of prions in a mouse neuroblastoma cell culture line (Proceedings of the National Academy of Sciences 2001;98:9836-41.).

    News media have disclosed that two patients have already begun treatment and that one of them, Rachel Forber, …

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