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First cases of human germline genetic modification announced

BMJ 2001; 322 doi: https://doi.org/10.1136/bmj.322.7295.1144 (Published 12 May 2001) Cite this as: BMJ 2001;322:1144
  1. Annabel Ferriman
  1. BMJ

    Scientists in the United States have reported the first cases of human germline genetic modification resulting in normal healthy children (Human Reproduction 2001;16:513-6).

    They have created children with genes from three different people—the children's parents and from women donors, part of whose egg cells were used in the in vitro fertilisation treatment. They admit that the resulting genetic modification could be passed on to future generations.

    The scientists, from the Institute for Reproductive Medicine and Science at St Barnabas in New Jersey, said that 30 babies worldwide have been …

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