Patients with breast cancer can stop tamoxifen after five yearsBMJ 2001; 322 doi: https://doi.org/10.1136/bmj.322.7295.1140 (Published 12 May 2001) Cite this as: BMJ 2001;322:1140
- Scott Gottlieb
- New York
Women who have had breast cancer gain no benefit from taking tamoxifen for longer than five years, a new study has found.
The researchers randomly assigned 1172 women who had already taken tamoxifen for five years to continue taking either the drug or a placebo. For seven years after randomisation, a slight advantage was observed in women who discontinued tamoxifen compared with those who continued to receive it (disease-free survival 82% v 78%; P=0.03, …