Scientists isolate HIV blocker in placentaBMJ 2001; 322 doi: https://doi.org/10.1136/bmj.322.7287.636/b (Published 17 March 2001) Cite this as: BMJ 2001;322:636
- Scott Gottlieb
- New York
Scientists have isolated a powerful blocker of HIV that is produced in the placenta and may one day be used to prevent mother to child transmission of the virus.
Scientists have known that the molecule, called leukaemia inhibitory factor, has a key role in maintaining pregnancy and in blastocyst implantation, but its potential for inhibiting HIV has not been discovered before now, said Dr Bruce Patterson from the Children's Memorial Hospital in Chicago, Illinois, and associates (Journal of Clinical Investigation 2001;107:287-94).
The researchers looked at levels of leukaemia inhibitory factor in the placentas of HIV positive women who had transmitted …
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