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Small rise in vitamin C intake could greatly reduce heart disease

BMJ 2001; 322 doi: http://dx.doi.org/10.1136/bmj.322.7286.576/b (Published 10 March 2001) Cite this as: BMJ 2001;322:576
  1. Jacqui Wise
  1. London

    Just a small increase in vitamin C intake could produce a substantial reduction in cardiovascular mortality, the authors of a prospective study have concluded.

    Professor Kay-Tee Khaw and colleagues from Cambridge University measured plasma ascorbic acid concentrations in 19 496 men and women aged 45–79 years and followed them up for four years (Lancet 2001;357:657-63).

    An increase in plasma ascorbic acid concentration was strongly and independently associated with a reduction in mortality from all causes, cardiovascular disease, and ischaemic heart disease. Vitamin C was also associated with a decreased risk of death related to cancer in men.

    The results showed a clear dose-response relation. …

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