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Dutch investigate if carcinogenic effects of diethylstilbestrol persist

BMJ 2001; 322 doi: https://doi.org/10.1136/bmj.322.7282.318/a (Published 10 February 2001) Cite this as: BMJ 2001;322:318
  1. Tony Sheldon
  1. Utrecht

    The Dutch Cancer Institute has launched the largest ever study into the long term effects of prescribing the hormone diethylstilbestrol (DES) to pregnant women.

    During the next four years the institute is to investigate 17 000 postmenopausal women whose mothers were prescribed the synthetic oestrogen in the belief that it prevented miscarriage. The drug was prescribed from 1947 until 1975, and an estimated 110 000 girls were born to mothers who took it. …

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