Letters

Can we trust elderly donor grafts for corneal transplantation?

BMJ 2001; 322 doi: https://doi.org/10.1136/bmj.322.7278.108 (Published 13 January 2001) Cite this as: BMJ 2001;322:108
  1. Carsten H Meyer (meyer027@mc.duke.edu), research fellow,
  2. Maya F Müller, attending physician,
  3. Hans-Jürgen Meyer, professor (emeritus)
  1. Department of Ophthalmology, Duke University Medical Center, Durham, NC 27710, USA
  2. Department of Ophthalmology, Medical University Lübeck, D-23538 Lübeck, Germany
  3. Department of Ophthalmology, Marienhospital Osnabrück, D-49074 Osnabrück, Germany

    EDITOR—Davis described the general increasing demand for donor organs in the United States and worldwide.1 Ophthalmology has special problems in this regard as corneal penetrating keratoplasty has become one of the most widely performed transplantations. Worldwide estimates are of 100 000 transplants performed annually, including 40 000 in the United States and 3500-4500 in Germany. The requirements for donor tissue exceed currently available tissue 20-fold.2

    Younger corneas are preferred as they generally have more endothelial cells. This non-replicating endothelium is essential for the …

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