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BAX gene needed for NSAIDs chemoprotection

BMJ 2000; 321 doi: https://doi.org/10.1136/bmj.321.7270.1173/a (Published 11 November 2000) Cite this as: BMJ 2000;321:1173
  1. Abi Berger
  1. BMJ

    Scientists have discovered how non-steroidal anti-inflammatory drugs (NSAIDs) can prevent colorectal cancer. Dr Lin Zhang and colleagues at the Howard Hughes Medical Institute and Johns Hopkins University in Baltimore have shown that a vital key to chemoprevention is the presence of the BAX gene (Science 2000;290:989-92).

    Long term use of NSAIDs is known to be effective in preventing colorectal cancer in those who …

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