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Susceptibility to infection

BMJ 2000; 321 doi: https://doi.org/10.1136/bmj.321.7268.1088/a (Published 28 October 2000) Cite this as: BMJ 2000;321:1088
  1. Douglas Carnall (dcarnall@bmj.com)
  1. BMJ

    It is interesting why the cystic fibrosis gene should be so common, when the effect of being homozygous for the gene is so devastating. In the late 1980s it was found that heterozygous possession may convey some protection against cholera (www.people.virginia.edu/~rjh9u/cysfib.html), analogous to the effects of the sickle cell gene and malaria.

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