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Personalised medicine comes a step closer for asthma

BMJ 2000; 321 doi: https://doi.org/10.1136/bmj.321.7263.724 (Published 23 September 2000) Cite this as: BMJ 2000;321:724
  1. Scott Gottlieb
  1. New York

    Researchers have discovered subtle differences in the DNA of people with asthma which help to predict which patients will benefit most from a certain drug before they take it, a new study has reported.

    In tests of the DNA of 121 patients with asthma, researchers led by Dr Stephen Liggett, professor of medicine at the University of Cincinnati College of Medicine, and colleagues found four different patterns of DNA in a gene that helps to relax muscles in a person's lungs. Lung function was measured before and after treatment with salbutamol (known as albuterol in the United States), with the individual responses …

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