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Thrombolytic agents no benefit to those over 75

BMJ 2000; 320 doi: https://doi.org/10.1136/bmj.320.7247.1428 (Published 27 May 2000) Cite this as: BMJ 2000;320:1428
  1. Scott Gottlieb
  1. New York

    Thrombolytic agents, currently promoted as the best emergency treatment for patients with myocardial infarction, do not benefit those who are aged 75 years and over and may actually increase their risk of adverse reactions and death, according to a new study.

    The study, by a research team at Johns Hopkins University, Baltimore, Maryland, looked at almost 8000 Medicare patients aged 65 to 86 years who had had heart attacks. Those aged under 75 receiving thrombolysis had a 6.8% death rate 30 days after the heart attack, compared with nearly 10% in …

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