Scientists build a peptide to stop toxic shock syndrome

doi:10.1136/bmj.320.7240.958

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Judy Siegel-Itzkovich

Jerusalem

A potential weapon against the virulent strains of staphylococcal and streptococcal bacteria that produce toxic shock syndrome has been developed by Israeli researchers and has been found to be effective in mice.

The research team, whose breakthrough is described in this month's Nature Medicine (2000;6:414-21) was headed by Raymond Kaempfer, professor of molecular virology at the Hebrew University-Hadassah faculty of medicine in Jerusalem. He and Dr Gila Arad, Revital Levy, and Dalia Hillman spent four years planning and building a synthetic peptide antagonist that blocks …