News

COX 2 inhibitors can affect the stomach lining

BMJ 1999; 319 doi: http://dx.doi.org/10.1136/bmj.319.7224.1518 (Published 11 December 1999) Cite this as: BMJ 1999;319:1518
  1. Deborah Josefson
  1. San Francisco

    A new class of analgesics designed to be less ulcerogenic than traditional non-steroidal anti-inflammatory drugs may not protect the gastric lining after all, according to a University of California study (Nature Medicine 1999;5:1415-23, 1348-9).

    Their ulcerogenic effect may stem from their antiangiogenic properties, and as such they may be useful anticancer drugs.

    The analgesics, agents known as selective cyclo-oxygenase-2 (COX 2) inhibitors, were specifically designed to be less harmful to the gastric mucosal …

    View Full Text

    Sign in

    Log in through your institution

    Free trial

    Register for a free trial to thebmj.com to receive unlimited access to all content on thebmj.com for 14 days.
    Sign up for a free trial

    Subscribe