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Apo E4 gene linked to breast cancer

BMJ 1999; 319 doi: https://doi.org/10.1136/bmj.319.7211.662b (Published 11 September 1999) Cite this as: BMJ 1999;319:662
  1. Janice Hopkins Tanne
  1. New York

    Scientists at the University at Buffalo, New York, have found a possible link between a variant of the apolipoprotein E (apo E) gene and breast cancer. The gene, which is involved in lipid metabolism, has three variants: apolipoprotein E2, E3 and E4.

    The apolipoprotein E4 variant is associated with raised concentrations of cholesterol and triglycerides …

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