Apo E4 gene linked to breast cancerBMJ 1999; 319 doi: https://doi.org/10.1136/bmj.319.7211.662b (Published 11 September 1999) Cite this as: BMJ 1999;319:662
- Janice Hopkins Tanne
- New York
Scientists at the University at Buffalo, New York, have found a possible link between a variant of the apolipoprotein E (apo E) gene and breast cancer. The gene, which is involved in lipid metabolism, has three variants: apolipoprotein E2, E3 and E4.
The apolipoprotein E4 variant is associated with raised concentrations of cholesterol and triglycerides …