Letters

Spacer devices increase dose of inhaled corticosteroids delivered

BMJ 1999; 318 doi: https://doi.org/10.1136/bmj.318.7200.1764 (Published 26 June 1999) Cite this as: BMJ 1999;318:1764
  1. Owen J Dempsey, Clinical research fellow (o.dempsey@dundee.ac.uk),
  2. Andrew M Wilson, Clinical lecturer,
  3. Brian J Lipworth, Professor of allergy and respiratory medicine
  1. Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital and Medical School, Dundee DD1 9SY

    EDITOR—In their editorial O'Callaghan and Barry highlight several important points regarding the use of inhaled corticosteroids.1 We wish to clarify two important statements that they make.

    It is incorrect to state that use of a spacer device with a pressurised metered dose inhaler does not affect the dose delivered to the airway. In vitro data showed that a 750 ml spacer device (Nebuhaler) increased the respirable fraction …

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