Sponsored trials do not necessarily give more-favourable resultsBMJ 1999; 318 doi: http://dx.doi.org/10.1136/bmj.318.7200.1762a (Published 26 June 1999) Cite this as: BMJ 1999;318:1762
- J N S Matthews, Professor of medical statistics ([email protected])
- Department of Statistics, University of Newcastle, Newcastle upon Tyne NE1 7RU
EDITOR—Wahlbeck and Adams report a review of randomised studies comparing clozapine with other antipsychotic drugs in schizophrenia.1 They argue thattrials that reported some connection with the manufacturer of clozapine (sponsored trials) were associated with more-favourable outcomes for the drug than were trials in which no such connection could be discerned (non-sponsored trials). Unfortunately, the information that the authors present does …
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