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Trial of steroids for treating head injury begins

BMJ 1999; 318 doi: https://doi.org/10.1136/bmj.318.7196.1441 (Published 29 May 1999) Cite this as: BMJ 1999;318:1441
  1. Zosia Kmietowicz
  1. London

    A major international trial has been launched to determine whether the delivery of cortico-steroids shortly after head injury can reduce deaths and disability after accidents.

    Corticosteroid randomisation after significant head injury (CRASH) is an international, multicentre trial, in which 20000 people with a recent head injury and impaired consciousness will be randomised to receive a 48 hour infusion of corticosteroids or placebo. …

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