Albumin again

doi:10.1136/bmj.318.7194.1352a

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Peter Horsey, Honorary consultant anaesthetist (horsey@rhchlib.demon.co.uk)

Shackleton Department of Anaesthetics, Southampton General Hospital, Southampton SO16 6YD

EDITOR—There are only two explanations for the conclusions of the Cochrane review of human albumin administration in critically ill patients—either that albumin was given in excessive amounts or that the commercial processing it undergoes makes it toxic. Several correspondents writing about the review call for expert appraisal of the evidence on which it was based.1

As a start I suggest that attention should be directed …