General PracticeCross sectional study of symptom attribution and recognition of depression and anxiety in primary careCommentary: There must be limits to the medicalisation of human distress

BMJ 1999; 318 doi: http://dx.doi.org/10.1136/bmj.318.7181.436 (Published 13 February 1999)
Cite this as: BMJ 1999;318:436

Cross sectional study of symptom attribution and recognition of depression and anxiety in primary care

  1. David Kessler, honorary research fellow (DavidKessler1{at}compuserve.com)a,
  2. Keith Lloyd, senior lecturerb,
  3. Glyn Lewis, professor of community and epidemiological psychiatryc,
  4. Dennis Pereira Gray, professor of general practicea
  1. a Institute of General Practice, Postgraduate Medical School, University of Exeter, Exeter EX2 5DW
  2. bDepartment of Mental Health, University of Exeter, Wonford House Hospital, Exeter EX2 5AF
  3. cDivision of Psychological Medicine, University of Wales College of Medicine, Cardiff CF4 4XN
  4. Caversham Group Practice, London NW5 2UP
  1. Correspondence to: Dr Kessler Gaywood House Surgery, North Street, Bristol BS3 3AZ

    Abstract

    Objectives: To examine the effect of patients' causal attributions of common somatic symptoms on recognition by general practitioners of cases of depression and anxiety and to test the hypothesis that normalising attributions make recognition less likely.

    Design: Cross sectional survey.

    Setting: One general practice of eight doctors in Bristol.

    Subjects: 305 general practice attenders.

    Main outcome measure: The rate of detection by general practitioners of cases of depression and anxiety as defined by the general health questionnaire.

    Results: Consecutive attenders completed the general health questionnaire and the symptom interpretation questionnaire, which scores style of symptom attribution along the dimensions of psychologising, somatising, and normalising. General practitioners detected depression or anxiety in 56 (36%; 95% confidence interval 28% to 44%) of the 157 patients who scored highly on the general health questionnaire. Subjects with a normalising attributional style were less likely to be detected as cases; doctors did not make any psychological diagnosis in 46 (85%; 73% to 93%) of 54 patients who had high questionnaire and high normalising scores. Those with a psychologising style were more likely to be detected; doctors did not detect 21 (38%; 25% to 52%) of 55 patients who had high questionnaire and high psychologising scores. The somatisation scale was not associated with low detection rates. This pattern of results persisted after adjustment for age, sex, general health questionnaire score, and general practitioner.

    Conclusions: Normalising attributions minimise symptoms and are non-pathological in character. The normalising attributional style is predominant in general practice attenders and is an important cause of low rates of detection of depression and anxiety.

    Key messages

    • Many patients with psychological disorders present to their general practitioner with common somatic symptoms. This combination has been referred to as “somatisation” and is associated with lower rates of diagnosis of depression and anxiety

    • When questioned directly about the cause of their symptoms most patients choose “normalising” attributions, which tend to minimise the importance of the symptoms; somatising attributions are uncommon

    • The more normalising attributions patients choose, the less likely are general practitioners to diagnose depression or anxiety; the association remain after adjustment for age, sex, general health questionnaire score, and which doctor the patient saw

    • The normalising attributional style makes a considerable contribution to the non-detection of depression and anxiety. A better understanding of how depressed patients view their symptoms may be the key to understanding low diagnostic rates

    Introduction

    Recognition of depression and anxiety is a key issue in general practice. If these disorders are not recognised they cannot be treated. There are a number of treatments of proved efficacy 1 2 and some evidence to show that recognition improves outcome, 3 4 though this has been questioned.5

    Most episodes of depression and anxiety—the “common mental disorders”—are contained and managed in primary care.6 Yet less than half of these episodes are identified in the consultation.7 Why is recognition of depression and anxiety such a problem in general practice? Doctors' skills and attitudes play a part. Certain key skills in the consultation have been identified that are both teachable and associated with increased rates of recognition.8 Teaching better consultation skills, however, leads to only a modest increase in detection rates.

    Most consultations in primary care are initiated by the patient. The content of the typical primary care consultation and its outcome will be influenced by what the patient chooses to present and how he or she chooses to present it.9 Common somatic symptoms are the currency of general practice; they are also concomitants of anxiety and depression.10 Numerous studies have categorised this combination of mood disorder and somatic symptomatology as “somatisation” and have shown it reduces general practitioners' ability to identify mental disorder. 10 11 But this use of the term somatisation has certain disadvantages in the context of primary care. It associates a common mode of presentation with the much rarer, more serious, chronic, and treatment resistant “somatisation disorder.”12 It also implies that patients who present with psychological disorders and common bodily symptoms tend to think of themselves as physically ill. Attempts to redefine somatisation for primary care have led to a confusion of multiple and at times complex definitions. 10 11 13 One way to simplify the issue is to ask patients themselves for their causal attributions for common somatic symptoms.

    Patients' beliefs about their symptoms are powerful influences on their decision to consult a doctor and how they present their problem when they do consult.14 In other words, do we think our fatigue is caused by emotional exhaustion? Is it due to anaemia? Or could it be because we have been overdoing it or not doing enough exercise? In the example given above three types of explanation or attribution have been offered for a common somatic symptom, fatigue. The first, the idea that it is due to emotional exhaustion, can be called a psychologising attribution. The second, that it is caused by anaemia, is a somatising attribution. In the third explanation the experience of fatigue is thought to be related to overexertion or not exercising enough. This type of attribution has been called normalising.15

    Until now most studies that have looked at patients' beliefs about their symptoms have focused on the dichotomy between somatising and psychologising. These are, in effect, “illness beliefs.” Normalising attributions are qualitatively different in that they are non-pathological. They are the most prevalent attribution in primary care attenders as well as in the population as a whole.15 This study asks whether such attributions have any effect on the general practitioner's ability to make a diagnosis of depression or anxiety. In particular it tests the hypothesis that normalising attributions reduce the likelihood of the detection of such disorders.

    Methods

    The study took place in an eight partner urban practice which serves 12 800 patients and has a slightly larger than average population of patients aged over 75. Surgeries were selected to ensure that both morning and evening attenders were represented and that all doctors were covered by the study. Consecutive attenders aged over 16 years were given two questionnaires before seeing their general practitioner. Twenty four questionnaires were incomplete, and 26 patients declined to participate.

    The 12 item general health questionnaire has been widely used to detect psychiatric disorder in primary care16 and validated in comparison with more detailed assessments. In a recent study it was compared with a more detailed psychiatric assessment and the optimal threshold for “caseness” found to be a score of 3 or more.17 We have adopted this definition of a case of psychological disorder.

    The symptom interpretation questionnaire is a self report questionnaire consisting of a list of 13 common bodily symptoms or sensations.15 Attached to each symptom are three possible explanations, each one corresponding to one of the three styles of attribution: psychologising, somatising, or normalising. The patients were asked to choose one explanation for each symptom, giving each subject a numerical score from 0-13 along the three attributional dimensions. The sum of all three scales was therefore 13. Subjects were classified as predominantly normalisers, psychologisers, or somatisers if they scored 7 or more on that scale. Validation research has shown that these scores remain reasonably consistent over time, supporting the theory that they may reflect underlying health beliefs.15

    General practitioners, who were blind to the results of the questionnaires, were asked to report any diagnoses of depression or anxiety they made and to note whether this was a new diagnosis or if the patient was already under treatment. The proportion of patients diagnosed as anxious or depressed was calculated according to scores on the normalising, psychologising, and somatising scales of the symptom interpretation questionnaire. For presentation purposes the scores were divided into four categories, but the scales were also examined as continuous variables. Logistic regression was used to estimate odds ratios for the detection of psychiatric disorder and to adjust for the confounding variables of age, sex, general health questionnaire score, and general practitioner consulted (as a categorical variable). Results were unchanged when data from the subjects who were “false positives” on the general health questionnaire were excluded. Statistical analysis was done with STATA.18 Ethical approval was obtained from the local research ethics committee.

    Results

    There were 225 women and 80 men in the study, a ratio of 2.8:1. The mean (range) age was 44 (16-90) years. The men were significantly older than the women (mean age 49.2 v 42.0 years; P<0.003). On the general health questionnaire 157 (52%; 95% confidence interval 46% to 57%) of all the attenders scored 3 or more. The general practitioners made a diagnosis of depression in 57 (19%; 15% to 24%) patients and anxiety in 14 (5%; 3% to 8%). Measured against the general health questionnaire threshold of 3 or more the general practitioners showed a specificity of 80% (69% to 89%) and a sensitivity of 57% (50% to 63%). There were 14 false positive results: patients who were diagnosed as depressed or anxious by the general practitioner but scored less than 3 on the general health questionnaire. Of these, seven had already been diagnosed with depression by a general practitioner and were receiving treatment.

    In the symptom interpretation questionnaire the normalising attribution was most often selected, with 146 out of 305 (48%) choosing seven or more normalising explanations out of a possible 13. Seventy one patients (23%) selected seven or more psychologising explanations, and only 16 patients (5%) chose seven or more somatising attributions (table 1). This pattern of distribution was also found in the initial validation studies.15 High scorers on the somatisation scale were older, normalisers younger (F3,301=3d7.54; P<0.0001). Psychologisers were more likely to be female and normalisers and somatisers to be male (likelihood ratio χ P<0.01).

    View this table:
    Table 1

    Detection by general practitioner of anxiety and depression in 305 patients with different styles of symptom attribution

    Symptom interpretation questionnaire and general practitioner diagnosis of anxiety and depression

    Table 2 shows that the higher the patient's score on the normalising dimension of the symptom interpretation questionnaire the less likely the general practitioner was to diagnose depression or anxiety (P<0.0001) and that the higher the patient's score on the psychologising dimension the more likely was the general practitioner to diagnose depression or anxiety (P<0.0001). For normalising and psychologising the relation was still present after adjustment for age, sex, general health questionnaire score, and which doctor the patient saw. There was no evidence of an association between detection by the general practitioner and the patient's somatising score (table 2). This lack of relation was confirmed by using somatisation as a continuous variable (likelihood ratio χ2=0.19; df=3D1; P=3D0.7).

    View this table:
    Table 2

    Detection by general practitioner (GP) of anxiety and depression in 305 patients with different degrees of normalising, psychologising, and somatising symptoms

    Recognition of anxiety and depression in general health questionnaire cases with different symptom attributional styles

    General practitioners did not diagnose depression or anxiety in 21 (38%; 25% to 52%) of the 55 patients who were cases according to the general health questionnaire and had a predominantly psychologising style of symptom attribution. In contrast depression or anxiety went undetected in 46 (85%; 73% to 93%) of the 54 patients who were cases according to the general health questionnaire but had a predominantly normalising style of symptom attribution (see table 1). There was no evidence that the association between normalising style and low rates of detection was influenced by score on the general health questionnaire (test for interaction, likelihood ratio χ2=0.19, df=3D1, P=3D0.66). Patients with a normalising style were less likely to be detected even when the analysis was restricted to those with a score of 7 or more.

    Discussion

    We found that different styles of symptom attribution are strongly associated with different rates of detection of depression and anxiety. Patients who make psychologising attributions are more likely to get a psychological diagnosis; the stronger their tendency to make such attributions the more likely such a diagnosis becomes. A normalising style of attribution has the opposite effect, and the stronger a patient's tendency to normalise or minimise his or her symptoms the less likely he or she is to be seen as depressed or anxious by the general practitioner. Somatising attributions, which are the least common, had no measurable effect on diagnostic rates, though this may have been because of lack of statistical power.

    Normalising attributions are the most common both in studies of populations and primary care attenders.15 Even among those with a high general health questionnaire score there are large numbers of “normalisers.” It is in this group, who tend to be younger and male, that general practitioners particularly did not detect depression and anxiety. Only eight out of 54 patients with a normalising attributional style and a high general health questionnaire score were diagnosed as being depressed or anxious. Forty six of the 101 (45.5%; 35.6% to 55.8%) undetected cases had a predominantly normalising style of attribution. Does this strong association between a normalising style of attribution and low rates of detection of mental disorder represent a causal relation? Our study suggests that it does. The association is robust and remains strong even after adjustment for which general practitioner the patient saw, general health questionnaire score, age, and sex. One limitation of the study is that we were not able to adjust for presenting symptom, but we might expect this to be influenced by causal attributional style. The normalising style arises out of the “discounting principle.”19 This is the idea that symptoms are often “explained away” as being caused by a minor environmental irritant or as the result of “overdoing it.” Such explanations propose a non-pathological cause for the symptom. In other words “normalisers” play down the significance of their symptoms. For the general practitioner to respond to the patient's own attribution of his or her symptoms is an expression of empathy and an important part of the negotiation between patient and doctor in moving towards a diagnosis. Such negotiations are the cornerstone of the doctor-patient relationship in general practice. Thus a psychological style of attribution is likely to elicit questions from the doctor about mental wellbeing and mood state and would favour a psychological formulation for the problem. In contrast, a normalising attribution, with its powerful “commonsensical” overtones, may influence the doctor to join with the patient in minimising and even dismissing the symptoms.

    It is easy to understand why people who make a somatising attribution for their symptoms would seek the advice of their general practitioner. It is also clear that the general practitioner is the first port of call for many in psychological distress. But when “normalising” attributions are concerned there seems to be a paradox. Why should someone who is making a normalising attribution seek a doctor's advice? The answer may lie in a need to check the normalising style of attribution and to be reassured that it is the correct one. If this is so, then the implicit question that the normaliser asks the physician is “there's nothing really wrong with me, is there?” In the same way that we respond to somatisers and psychologisers by accepting their attribution, so we may respond to the normalisers by agreeing with them. This collusion could result in a tendency to neglect symptoms of depression and anxiety.

    The rate of apparent underdiagnosis of psychological disorder in primary care remains stubbornly high. Patients with such disorders may often present with somatic symptoms but are rarely committed “somatisers.” Instead they are more likely to be normalising their symptoms and giving them a non-pathological attribution. The question of whether such patients would benefit from detection could be examined by a comparison of outcomes for detected and undetected depressed patients with different attributional styles.

    Acknowledgments

    With thanks to the patients, doctors, and staff at Horfield Health Centre, Bristol.

    Contributors: DK had the original idea for the study, which was developed in discussions with KL and DPG. These three designed the study. DK undertook the data collection. DK, KL, and GL analysed the data. DK drafted the paper, which was edited by GL. DK is the guarantor.

    Funding: DPG was funded by the NHS Executive to undertake research on depression.

    Competing interests: None declared.

    References

    Commentary: There must be limits to the medicalisation of human distress

    1. Iona Heath, general practitioner (pe31{at}dial.pipex.com)
    1. a Institute of General Practice, Postgraduate Medical School, University of Exeter, Exeter EX2 5DW
    2. bDepartment of Mental Health, University of Exeter, Wonford House Hospital, Exeter EX2 5AF
    3. cDivision of Psychological Medicine, University of Wales College of Medicine, Cardiff CF4 4XN
    4. Caversham Group Practice, London NW5 2UP

      This paper sets out to elucidate further the much reported “failure” of general practitioners to diagnose depression. The 12 item general health questionnaire was administered to 305 consecutive patients attending general practice, and the threshold for the diagnosis of depression was set at a score of 3 or more, which meant that a staggering 51.5% of the patients were considered by the researchers to have measurable depression. This extraordinary finding does not seem to have disturbed them. The patients' general practitioners made a diagnosis of depression or anxiety in only 23% of the attenders, but this is still a huge proportion of unselected patients from a waiting room. None the less, the paper reports these figures as showing a significant and serious failure to diagnose.

      The patients were also given a questionnaire which enabled them to be divided into three categories: those who tend to find psychological explanations for their symptoms, those who find physical explanations, and those who tend to normalise their symptoms by finding explanations in their life circumstances. The major finding of the paper is that general practitioners are much more likely to “fail” to diagnose depression in patients who tend to normalise their symptoms. Surely this conclusion provides us with a superlative example of the folly of medicalisation.1

      The general health questionnaire includes the following questions. In the past few weeks, have you been able to concentrate on whatever you're doing? been able to enjoy your normal day to day activities? been feeling reasonably happy, all things considered? By setting the threshold for caseness at 3, the researchers will have defined as depressed all those who answered “less so than usual” to all of these three questions or any other three questions out of the full range of 12.

      Patients come to the general practitioner for many reasons but most commonly because they are disturbed or distressed. They may be in pain, and they may be worried that their symptoms are the first indication of serious or life threatening disease. They may have lost someone close, their job may be under threat, their partner may have hit them, or their home may be damp or frightening or overcrowded. Any such patient is likely to answer “less so than usual” to the three questions but is it helpful to consider them as depressed?

      Human beings struggle to make sense of suffering and illness by finding meaning for it in the very particular context of each individual life. Patients who normalise their experience may have already begun this process of finding meaning, making sense, and learning to cope.2 Do we have any evidence that the medical treatment of depression improves outcomes to an extent which would justify pressurising patients into accepting psychiatric explanations for symptoms they are willing to normalise? What evidence we do have suggests that the depression which is apparently missed by general practitioners runs a relatively benign and self limiting course.3

      General practitioners should not be castigated when they try, alongside the patient, to find out what is the matter rather than to make a diagnosis.4

      References

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