Link between breast cancer and ATM gene is strong

doi:10.1136/bmj.318.7180.400

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Michael Swift, Director,
Yun Su, Epidemiologist

Institute for the Genetic Analysis of Common Diseases, New York Medical College, Hawthorne, New York 10532, USA

EDITOR—We welcome Lavin's recognition of the important role that the ataxia-telangiectasia (ATM) gene plays in breast cancer despite the attention given to two other genes, BRCA1/BRCA2, which are numerically less important.1 It is important to emphasise that the evidence linking the ataxia-telangiectasia gene to breast cancer is more than suggestive. As well as the two smaller studies referenced by Lavin, two large epidemiological studies have clearly …