Randomised block design is more powerful than minimisation

BMJ 1999; 318 doi: http://dx.doi.org/10.1136/bmj.318.7178.263 (Published 23 January 1999) Cite this as: BMJ 1999;318:263
  1. N Ross, Research assistant
  1. Pain Relief Foundation, Liverpool L9 1AE

    EDITOR—I agree with Treasure and MacRae that the greatest determinant of the power of a study is its design.1 Minimisation improves power by comparing similar groups but there is a similar technique—randomised block design—which has even more power.2

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