Technical ability to treat male factor infertility must not overtake academic knowledge

BMJ 1998; 317 doi: https://doi.org/10.1136/bmj.317.7162.888 (Published 26 September 1998) Cite this as: BMJ 1998;317:888
  1. M Rafet Gazvani, Research fellow,
  2. David H Richmond, Consultant in obstetrics and gynaecology,
  3. Peter J Howard, Consultant in clinical genetics,
  4. Charles R Kingsland, Consultant in obstetrics and gynaecology,
  5. D Iwan Lewis-Jones, Consultant andrologist
  1. Liverpool Women's Hospital, Liverpool L8 7SS

    EDITOR—We were alarmed by Kurinczuk et al's findings that infants born after intracytoplasmic sperm injection are twice as likely as other infants to have a major birth defect and nearly 50% more likely to have a minor defect.1 Our unit has been concerned about the safety of intracytoplasmic sperm injection,2 and this concern has been voiced by other units. We previously suggested that routine karyotyping should …

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