Vaccine delivery system using safe bacteria inventedBMJ 1998; 317 doi: https://doi.org/10.1136/bmj.317.7159.620b (Published 05 September 1998) Cite this as: BMJ 1998;317:620
- Abi Berger, science correspondent
Scientists in Paris have invented a way of delivering DNA into cells without relying on pathogenic bacteria.
Bacteria have only recently been used for DNA delivery (in gene therapy and DNA vaccines), and up to now only attenuated bacteria (those with diminished pathogenicity) have been used. Now Catherine Grillot-Courvalin and her team at the Pasteur Institute have worked out a way of using bacteria that are unable to grow in conventional media and are thus considered non-pathogenic (Nature Biotechnology …