Two sets of papers in this week's issue discuss the effects of extending boundaries in different ways. In Britain at least there have long been arguments about whether to extend the breast cancer screening programme beyond the age of 65. Older women weren't included in the original programme because cost effectiveness was thought to be low through low uptake and shorter life expectancy. But, as Gary Rubin and colleagues show on p 388, older women do turn up for screening, and many more cancers are detected.
In terms of cost …
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