Plans for future influenza pandemics must raise awareness of Reye's syndrome

doi:10.1136/bmj.317.7153.284

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Susan Hall, Consultant epidemiologist,
Richard Lynn, Scientific coordinator

Department of Paediatrics, Sheffield Children's Hospital, Sheffield S10 2TH
British Paediatric Surveillance Unit of the Royal College of Paediatrics and Child Health, London W1N 6DE

EDITOR—Walker and Christie report that the index patient in the outbreak of avian influenza in Hong Kong died of Reye's syndrome.1 Reye's syndrome was an important cause of death and severe neurological morbidity in the United States in the 1970s and early 1980s, particularly during influenza epidemics. Its incidence fell sharply after recognition of its association with aspirin and the introduction of public education and warning labelling on aspirin products.2 …