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Eosinophilic pneumonia induced by dapsone

BMJ 1998; 317 doi: https://doi.org/10.1136/bmj.317.7152.181 (Published 18 July 1998) Cite this as: BMJ 1998;317:181
  1. D Jaffuel,
  2. B Lebel,
  3. D Hillaire-Buys,
  4. J Pene,
  5. P Godard,
  6. F-B Michel,
  7. J-P Blayac,
  8. J Bousquet,
  9. P Demolyi
  1. Maladies Respiratoires and Centre Regional de Pharmacovigilance, Centre Hospitalier Universitaire de Montpellier, 34295 Montpellier Cedex 5, France

    Pulmonary eosinophilia can be caused by numerous drugs and may be life threatening. To our knowledge, only one case of eosinophilic pneumonia associated with dapsone has been reported.1 We report a case of pulmonary eosinophilia induced by dapsone and confirmed by unintentional rechallenge with the drug.

    A 60 year old woman with chronic urticaria was treated with dapsone (100 mg/day) in November 1994 because conventional treatment (H1 receptor antagonists and …

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