Streptoccocus infection linked with Tourette's syndromeBMJ 1998; 317 doi: https://doi.org/10.1136/bmj.317.7150.12b (Published 04 July 1998) Cite this as: BMJ 1998;317:12
- Deborah Josefson
- San Francisco
US researchers have uncovered evidence that Tourette's syndrome, a chronic debilitating neurological disorder, may have an immune mediated, infectious basis (Neurology 1998;50:1530-3).
Tourette's syndrome is characterised by multiple involuntary motor and vocal tics. Additionally, copralalia, the involuntary utterance of obscenities, often shouted, may occur. Since familial clustering occurs, Tourette's is thought to be genetic in origin. An autosomal dominant mode of inheritance has been proposed, but only a small number of those who inherit a single copy of the gene ever develop the syndrome.
Because of this discrepancy, Dr Harvey Singer and colleagues at the Johns Hopkins University School of Medicine …