Elective caesarean and zidovudine cuts HIV transmissionBMJ 1998; 317 doi: https://doi.org/10.1136/bmj.317.7150.11 (Published 04 July 1998) Cite this as: BMJ 1998;317:11
- Scott Gottlieb, Clegg scholar
Pregnant women who are HIV positive can dramatically reduce the likelihood of transmission of disease to their newborns by having an elective caesarean delivery while undergoing treatment with the antiretroviral drug zidovudine, according to a French study.
The prospective cohort study, release of which was timed to coincide with the 12th world AIDS conference in Geneva, involved 2834 children born to mothers with HIV-1 infection (JAMA 1998;280:55-60). The researchers, led by Laurent Mandelbrot of Cochin-Port Royal Hospital in Paris, found that of 133 children delivered to HIV infected mothers by elective caesarean section and in the presence of zidovudine prophylaxis, only one child (1%) was born …