Oral contraception was not associated with venous thromboembolic disease in recent study

BMJ 1998; 316 doi: https://doi.org/10.1136/bmj.316.7137.1090 (Published 04 April 1998) Cite this as: BMJ 1998;316:1090
  1. R D T Farmer, Professor,
  2. J-C Todd, Research assistant,
  3. K D MacRae, Reader,
  4. T J Williams, Research assistant,
  5. M A Lewis, Director
  1. Department of Public Health, Imperial College School of Medicine (University of London), London SW10 9NH
  2. Epidemiology Pharmacology and Systems Research, Berlin, Germany

    EDITOR—Three studies published in 1995-6 reported odds ratios for venous thromboembolic disease among women using third generation oral contraceptives compared with women using second generation products that were in the range 1.5 to 1.8.1-3 The design limitations and interpretation of the results of these studies have been widely questioned. A further study, based on computer records from 147 general practitioners in Britain, failed to show any significant difference in the risk of venous thromboembolic disease between generations of oral contraceptive.4

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