BMJ 1998; 316 doi: https://doi.org/10.1136/bmj.316.7130.562 (Published 14 February 1998) Cite this as: BMJ 1998;316:562

Two rare diseases which coexist more often than would be expected by chance are coeliac disease and primary biliary cirrhosis. A study in south Wales found that 3% of 143 patients with coeliac disease had biliary cirrhosis and 6% of 67 patients with biliary cirrhosis had coeliac disease (Gut 1998;42:120-2). Both diseases are detectable by antibody testing, and effective treatments are available. The criteria for screening are, therefore, satisfied.

The search continues for an effective oral treatment for impotence. A review in the British Journal of Urology (1998;81:122-7) looks at adrenergic receptor blockers, dopamine receptor agonists, serotonin blockers, nitric oxide precursors, and phosphodiesterase inhibitors and concludes that the death knell is sounding for pumps, injections, and implants—but the promising newer agents are still under trial.

Children born to mothers who develop postnatal depression have various adverse psychological outcomes. Some of these are apparent when they start school at the age of 5 (British Journal of Psychiatry 1998;172:58-63). A study of 61 women who had become depressed after childbirth followed up 55 until five years later. When their children were assessed by their teachers the boys with depressed mothers, but not the girls, were rated as hyperactive and easily distractible.

Vulvodynia, orchialgia, penile pain, and proctalgia fugax are just a …

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