Doctors volunteer to be guinea pigs for AIDS vaccine

BMJ 1997; 315 doi: (Published 04 October 1997) Cite this as: BMJ 1997;315:831
  1. Deborah Josefson
  1. San Francisco

    Some doctors, healthcare workers, and AIDS activists have said that they plan to test a live HIV vaccine on themselves in an effort to move forward the development of an AIDS vaccine.

    Fifty members of the Chicago based International Association of Physicians in AIDS Care (IAPAC) have volunteered for live virus vaccine trials. The group plans to use an attenuated strain of HIV engineered by Dr Ronald Desrosiers from Harvard University's school of medicine. This form of the virus is missing four genes thought to be essential for HIV replication and has shown efficacy in vaccine trials in primates.

    While …

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