BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7111.824 (Published 27 September 1997) Cite this as: BMJ 1997;315:824

The value of angiotensin converting inhibitors in non-diabetic renal disease is shown in a meta-analysis of 10 randomised controlled trials encompassing 1594 patients followed up for a minimum of one year (Annals of Internal Medicine1997;127:337-45). The pooled relative risk of patients taking the drugs developing end stage renal disease compared with controls was 0.70 (95% confidence interval 0.51 to 0.97), and there was no adverse effect on mortality in the treated patients.

Another report in the Annals of Internal Medicine (1997;127:372-5), compares endothelial dependent arterial dilatation in healthy smokers living in southern China with that in matched smokers from England and Australia. Unlike their white counterparts, Chinese smokers showed no smoking associated endothelial dysfunction. This may account for the low incidence of coronary heart disease in southern China despite high rates of smoking.

Working in an area of extreme deprivation might be expected to be associated with low morale, but a survey of 500 London general practitioners working in practices with widely different deprivation scores showed no such association (British Journal of General Practice 1997;47:547-52). Factors that did correlate with low wellbeing were subjective “stress” due to time pressures, and working in small practices with small healthcare teams.

A prospective study of 479 …

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