Hazards of running a marathon

doi:10.1136/bmj.315.7104.370

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41-Fold increase in creatine kinase has been reported

Ian A Laing, Consultant neonatologista

^a Royal Infirmary of Edinburgh, Edinburgh EH3 9YW
^b Department of Cardiology, Victoria Infirmary, Glasgow G42 9TY

Editor—The recent grand round from Hammersmith Hospital pointed out that, 24 hours after a marathon run, creatine kinase activity may be raised in the absence of myocardial infarction.1 The author recorded a total creatine kinase activity of 1800 IU/l 24 hours after a marathon, causing the registrar in chemical pathology who was on duty to think temporarily that the 61 year old runner might have had a myocardial infarction.

In 1984 I described my own experience of measuring multiple variables during a marathon run.2 The creatine kinase activity before the race was 83 IU/l, and at 8, …