Hazards of running a marathon

BMJ 1997; 315 doi: https://doi.org/10.1136/bmj.315.7104.370 (Published 09 August 1997) Cite this as: BMJ 1997;315:370

41-Fold increase in creatine kinase has been reported

  1. Ian A Laing, Consultant neonatologista
  1. a Royal Infirmary of Edinburgh, Edinburgh EH3 9YW
  2. b Department of Cardiology, Victoria Infirmary, Glasgow G42 9TY

    Editor—The recent grand round from Hammersmith Hospital pointed out that, 24 hours after a marathon run, creatine kinase activity may be raised in the absence of myocardial infarction.1 The author recorded a total creatine kinase activity of 1800 IU/l 24 hours after a marathon, causing the registrar in chemical pathology who was on duty to think temporarily that the 61 year old runner might have had a myocardial infarction.

    In 1984 I described my own experience of measuring multiple variables during a marathon run.2 The creatine kinase activity before the race was 83 IU/l, and at 8, …

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