Hopes raised for HIV vaccine

BMJ 1997; 314 doi: (Published 10 May 1997) Cite this as: BMJ 1997;314:1365
  1. Zosia Kmietowicz
  1. London

    American scientists have blocked the transmission of HIV-1 in chimpanzees with a new vaccine based on DNA. It is the first time anyone has managed to protect against HIV infection in the chimpanzee, the closest relative to humans in terms of immunological responses.

    The research team concludes that at the very least their study shows that their DNA vaccine is capable of “interrupting the establishment of persistent infection,” describing it as an “unprecedented” effect (Nature Medicine 1997;3:526-32).

    The HIV vaccine uses the genes of a weakened …

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