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Any questions: Is there a molecular explanation of heart rhyrhm?

BMJ 1997; 314 doi: http://dx.doi.org/10.1136/bmj.314.7091.0h (Published 10 May 1997) Cite this as: BMJ 1997;314:h
  1. Denis Noble, professor of cardiovascular physiology in Oxford

    Most physiological phenomena are now being explained at molecular or atomic level. What explains the regular action of the sinoauricular node, which initiates the contraction of the heart?

    The generation of the rhythm of the heart is a good example of a physiological function that cannot be explained at the molecular level. There is no molecular, still less an atomic, oscillator …

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