Drug delivery from inhaler devices

BMJ 1997; 314 doi: (Published 05 April 1997) Cite this as: BMJ 1997;314:990

An author's error occurred in this editorial by Hans Bisgaard (12 October 1996, pp 895-6). The fourth sentence in the third paragraph should have read: “During simulated breathing by a ventilator, the relative fine particle masses delivered by a pressurised metered dose inhaler plus a NebuChamber spacer (budesonide), an inhaler plus Babyhaler (fluticasone), and an inhaler plus AeroChamber (budesonide) were 2.5, 1.5, and 1 [not 1, 1.5, and 2.5] respectively.” The conclusion drawn in the editorial is correct–that is, “that the nominal dose for an inhaler plus AeroChamber should be 2.5 times higher than that for an inhaler plus NebuChamber to obtain the same clinical effect.”

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