Treatment of breast cancer before surgery will present pathologists with challenges

BMJ 1997; 314 doi: https://doi.org/10.1136/bmj.314.7082.755a (Published 08 March 1997) Cite this as: BMJ 1997;314:755
  1. P A Trott, Consultant pathologist,
  2. N Nasiri, Consultant pathologist
  1. a Department of Anatomical Pathology and Breast Unit, Royal Marsden Hospital, London SW3 6JJ

    Editor—Richard Epstein's editorial on treating breast cancer before carrying out surgery raises the question of how breast surgeons will feel about withholding lumpectomy from many of their patients with newly diagnosed cancer.1 Another, perhaps more important, question is how pathologists will feel. The best predictor of tumour behaviour is an assessment of tumour size, histopathological grade, and lymph node status. This has been established as a powerful indicator of prognosis, notably by a group …

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