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Fetal bone marrow transplants spark hope for genetic diseases

BMJ 1997; 314 doi: https://doi.org/10.1136/bmj.314.7075.165k (Published 18 January 1997) Cite this as: BMJ 1997;314:165
  1. Deborah Josefson
  1. Connecticut

    Several infants destined to develop the severe combined immunodeficiency syndrome have had their disease prevented by in utero bone marrow transplantation. The success of the technique may herald a new era in the treatment of some types of genetic disorders.

    The technique of fetal bone marrow transplantation was pioneered by Dr Alan Flake of the Children's Hospital of Philadelphia, and two cases are described in recent issues of the New England Journal of Medicine (1996:335:1806-10) and the Lancet (1996;348:1484-7). In both …

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