Education And Debate

First priority is to decrease the severity of hyperchylomicronaemia

BMJ 1997; 314 doi: (Published 04 January 1997) Cite this as: BMJ 1997;314:62
  1. Gilbert R Thompson, professor of clinical lipidologya
  1. a MRC Lipoprotein Team, Royal Postgraduate Medical School, Hammersmith Hospital, London W12 0NN


    This girl is acutely ill and in the first instance it is immaterial whether her hyperlipidaemia is primary or secondary. Her main requirement is for treatment which decreases the severity of the hyperchylomicronaemia as rapidly as possible. This is best achieved by plasma exchange using a continuous flow blood cell separator with heparin as the anticoagulant and 4.5% human albumin as the exchange medium.

    Heparin has the advantages over citrate that it is not hypocalcaemic and that it releases lipoprotein lipase into …

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