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HRT use in high risk women should be reviewed

BMJ 1996; 313 doi: https://doi.org/10.1136/bmj.313.7065.1102a (Published 02 November 1996) Cite this as: BMJ 1996;313:1102

Doctors should review whether women in high risk groups really need to take hormone replacement therapy, the Committee on Safety of Medicines has announced.

The announcement follows three papers published in the Lancet last month that found an increased risk of deep vein thrombosis or pulmonary embolism, or both, in women currently taking hormone replacement therapy (Lancet 1996;348:977-87). The relative risk of venous thromboembolism was raised twofold to fourfold in current users, which is greater than that among younger women who use …

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