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Prozac linked with minor birth defects

BMJ 1996; 313 doi: http://dx.doi.org/10.1136/bmj.313.7062.902 (Published 12 October 1996) Cite this as: BMJ 1996;313:902

Babies born to women taking the antidepressant fluoxetine (Prozac) in the third trimester of pregnancy may be at increased risk of minor abnormalities but show no increase in major problems, suggests new research.

Researchers from the University of California found that the incidence of three or more minor anomalies occurred in more than twice as many babies born to women taking fluoxetine (15.5%) than in controls (6.5%). However, the rate of spontaneous pregnancy loss and of major structural anomalies was the same in both groups, according to the research published in the New England Journal of Medicine (1996;335:1010-5).

The results came from analysing pregnancy …

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